2. Gene
  3. Tcirg1 - T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 Gene

Tcirg1 - T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as oc; Stv1; Vph1; Atp6i; OPTB1; TIRC7; ATP6a3; OC-116; ATP6N1C

Gene ID: 27060 | Gene type: protein coding

About Tcirg1

Summary

Predicted to enable ATPase binding activity. Acts upstream of or within several processes, including T cell activation; animal organ development; and cellular cation homeostasis. Located in several cellular components, including cytoplasmic vesicle; lysosome; and nucleus. Is expressed in several structures, including ciliary body; future brain; hemolymphoid system gland; metanephros; and optic choroid plus pigmented retinal epithelium. Used to study autosomal recessive osteopetrosis 1 and clubfoot. Human ortholog(s) of this gene implicated in autosomal recessive osteopetrosis 1. Orthologous to human TCIRG1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3). [provided by Alliance of Genome Resources, Apr 2022]

Tcirg1 Products(3)

mRNA Protein Name
NM_001136091.2 NP_001129563.1 V-type proton ATPase 116 kDa subunit a3
NM_001167784.1 NP_001161256.1 V-type proton ATPase 116 kDa subunit a3
NM_016921.3 NP_058617.3 V-type proton ATPase 116 kDa subunit a3
Protein Preferred Names Protein Names

V-type proton ATPase 116 kDa subunit a3

ATPase, H+ transporting, lysosomal I

V-ATPase a3

osteosclerotic

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14315 TCIRG1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21955 Tcirg1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tcirg1 NCBI NCBI:10312