Scube3 - signal peptide, CUB domain, EGF-like 3 Gene

Mus musculus

Also known as CEGF3; D030038I21Rik

Gene ID: 268935 | Gene type: protein coding

About Scube3

Summary

Predicted to enable identical protein binding activity. Acts upstream of or within positive regulation of smoothened signaling pathway. Predicted to be located in plasma membrane. Predicted to be active in cell surface and extracellular space. Is expressed in several structures, including alimentary system; embryo ectoderm; embryo mesenchyme; integumental system; and nose. Orthologous to human SCUBE3 (signal peptide, CUB domain and EGF like domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Scube3 Products(2)

mRNA	Protein	Name
NM_001004366.2	NP_001004366.1	signal peptide, CUB and EGF-like domain-containing protein 3 isoform 1 precursor
NM_001368734.1	NP_001355663.1	signal peptide, CUB and EGF-like domain-containing protein 3 isoform 2 precursor

Gene Ontology

Biological Process

Biological Process GO Annotation	Evidence	Reference	Source
involved in positive regulation of osteoblast differentiation	IMP IMP: Inferred from mutant phenotype	33308444	MGI
acts upstream of or within positive regulation of smoothened signaling pathway	IDA IDA: Inferred from direct assay	25639508	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

signal peptide, CUB and EGF-like domain-containing protein 3

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS21191	Scube3 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS12573	SCUBE3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Scube3	NCBI	NCBI:222663

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