2. Gene
  3. Adh4 - alcohol dehydrogenase 4 (class II), pi polypeptide Gene

Adh4 - alcohol dehydrogenase 4 (class II), pi polypeptide Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Adh2

Gene ID: 26876 | Gene type: protein coding

About Adh4

Summary

Enables NADPH:quinone reductase activity; alcohol dehydrogenase activity, zinc-dependent; and alditol:NADP+ 1-oxidoreductase activity. Involved in fatty acid omega-oxidation. Acts upstream of or within several processes, including alcohol catabolic process; ethanol metabolic process; and quinone metabolic process. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including adrenal cortex; genitourinary system; integumental system; limb; and nervous system. Orthologous to human ADH4 (alcohol dehydrogenase 4 (class II), pi polypeptide). [provided by Alliance of Genome Resources, Apr 2022]

Adh4 Products(1)

mRNA Protein Name
NM_011996.2 NP_036126.2 all-trans-retinol dehydrogenase [NAD(+)] ADH4
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables NADPH:quinone reductase activity IDA
IDA: Inferred from direct assay
10514444 MGI
enables alcohol dehydrogenase (NAD+) activity IDA
IDA: Inferred from direct assay
518534 MGI
enables aldose reductase (NADPH) activity IDA
IDA: Inferred from direct assay
10514444 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within alcohol catabolic process IDA
IDA: Inferred from direct assay
10514444 MGI
acts upstream of or within cellular aldehyde metabolic process IDA
IDA: Inferred from direct assay
10514444 MGI
acts upstream of or within ethanol metabolic process IDA
IDA: Inferred from direct assay
518534 MGI
involved in fatty acid omega-oxidation IDA
IDA: Inferred from direct assay
16081420 MGI
acts upstream of or within quinone metabolic process IDA
IDA: Inferred from direct assay
10514444 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

all-trans-retinol dehydrogenase [NAD(+)] ADH4

alcohol dehydrogenase II

alcohol dehydrogenase class II

class II type ADH

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00369 ADH4 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18599 Adh4 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25084 Adh4 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adh4 NCBI NCBI:127