Soat2 - sterol O-acyltransferase 2 Gene

Rattus norvegicus

Also known as Acat-2

Gene ID: 266770 | Gene type: protein coding

About Soat2

Summary

Enables sterol O-acyltransferase activity. Involved in Cholesterol metabolic process and response to nutrient. Located in endoplasmic reticulum. Used to study end stage renal disease. Biomarker of nephrotic syndrome. Human ortholog(s) of this gene implicated in coronary artery disease and hepatocellular carcinoma. Orthologous to human SOAT2 (sterol O-acyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Soat2 Products(1)

mRNA	Protein	Name
NM_153728.3	NP_714950.3	sterol O-acyltransferase 2

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables sterol O-acyltransferase activity	IDA IDA: Inferred from direct assay	12217884	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cholesterol metabolic process	IDA IDA: Inferred from direct assay	12217884	RGD
involved in response to nutrient	IEP IEP: Inferred from expression pattern	12563020	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

sterol O-acyltransferase 2

acyl-CoA:cholesterol acyltransferase 2	acyl-coenzyme A:cholesterol acyltransferase 2
cholesterol acyltransferase 2

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-117832	Pyripyropene A	Inhibitor	99.71%	Unkown
HY-RS13550	SOAT2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS19037	Soat2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS25526	Soat2 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Soat2	NCBI	NCBI:8435

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