2. Gene
  3. Clcn7 - chloride channel, voltage-sensitive 7 Gene

Clcn7 - chloride channel, voltage-sensitive 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as ClC-7; D17Wsu51e

Gene ID: 26373 | Gene type: protein coding

About Clcn7

Summary

Predicted to enable chloride transmembrane transporter activity. Predicted to be involved in response to pH. Predicted to act upstream of or within ion transport. Predicted to be located in cytoplasmic vesicle and nucleoplasm. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in several structures, including early conceptus; heart and pericardium; nervous system; oocyte; and submandibular gland primordium. Used to study autosomal dominant osteopetrosis 2 and autosomal recessive osteopetrosis 4. Human ortholog(s) of this gene implicated in autosomal dominant osteopetrosis 2 and autosomal recessive osteopetrosis 4. Orthologous to human CLCN7 (chloride voltage-gated channel 7). [provided by Alliance of Genome Resources, Apr 2022]

Clcn7 Products(2)

mRNA Protein Name
NM_001317404.1 NP_001304333.1 H(+)/Cl(-) exchange transporter 7 isoform 2
NM_011930.4 NP_036060.1 H(+)/Cl(-) exchange transporter 7 isoform 1
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
16525474 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

H(+)/Cl(-) exchange transporter 7

chloride channel 7 alpha subunit

chloride channel protein 7

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02759 CLCN7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20884 Clcn7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27401 Clcn7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clcn7 NCBI NCBI:1186