2. Gene
  3. mt-Nd5 - NADH dehydrogenase 5, mitochondrial Gene

mt-Nd5 - NADH dehydrogenase 5, mitochondrial Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus (strain: BN/SsNHsdMCW)

Also known as ND5

Gene ID: 26202 | Gene type: protein coding

About mt-Nd5

Summary

Predicted to enable NADH dehydrogenase (ubiquinone) activity. Involved in response to hydrogen peroxide; response to hypoxia; and response to organonitrogen compound. Located in neuron projection. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Leigh disease; and MELAS syndrome. Orthologous to human MT-ND5 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5). [provided by Alliance of Genome Resources, Apr 2022]

mt-Nd5 Products(2)

mRNA Protein Name
YP_665639.1 NADH dehydrogenase subunit 5 (mitochondrion) [Rattus norvegicus]
YP_665639.1 NADH dehydrogenase subunit 5 (mitochondrion) [Rattus norvegicus]
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in response to hydrogen peroxide IEP
IEP: Inferred from expression pattern
9788897 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
16257962 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NADH dehydrogenase subunit 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS21159 mt-Nd5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08801 MT-ND5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27675 mt-Nd5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens mt-Nd5 NCBI NCBI:4540