2. Gene
  3. mt-Co2 - cytochrome c oxidase II, mitochondrial Gene

mt-Co2 - cytochrome c oxidase II, mitochondrial Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus (strain: BN/SsNHsdMCW)

Also known as COII; COX2

Gene ID: 26198 | Gene type: protein coding

About mt-Co2

Summary

Predicted to enable copper ion binding activity. Predicted to contribute to cytochrome-c oxidase activity. Involved in several processes, including lactation; positive regulation of cellular biosynthetic process; and positive regulation of necrotic cell death. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex IV. Biomarker of colorectal carcinoma and type 2 diabetes mellitus. Orthologous to several human genes including MTCO2P12 (MT-CO2 pseudogene 12). [provided by Alliance of Genome Resources, Apr 2022]

mt-Co2 Products(1)

mRNA Protein Name
YP_665632.1 cytochrome c oxidase subunit II (mitochondrion) [Rattus norvegicus]
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in lactation IEP
IEP: Inferred from expression pattern
2557014 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
33310031 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome c oxidase subunit 2

cytochrome c oxidase subunit II

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08758 MT-CO2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20181 mt-Co2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26685 mt-Co2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens mt-Co2 NCBI NCBI:4513