Acp5 - acid phosphatase 5, tartrate resistant Gene

Rattus norvegicus

Also known as Trap; TTRRAP

Gene ID: 25732 | Gene type: protein coding

About Acp5

Summary

Enables Acid Phosphatase activity. Involved in several processes, including bone resorption; response to L-ascorbic acid; and response to Cholesterol. Located in extracellular space. Orthologous to human ACP5 (Acid Phosphatase 5, tartrate resistant). [provided by Alliance of Genome Resources, Apr 2022]

Acp5 Products(2)

mRNA	Protein	Name
NM_001270889.1	NP_001257818.1	tartrate-resistant acid phosphatase type 5 isoform 2 precursor
NM_019144.2	NP_062017.2	tartrate-resistant acid phosphatase type 5 isoform 1 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables acid phosphatase activity	IDA IDA: Inferred from direct assay	19854170	RGD
enables hydrolase activity	IDA IDA: Inferred from direct assay	11890682	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in bone resorption	IEP IEP: Inferred from expression pattern	20069278	RGD
involved in cellular response to zinc ion starvation	IEP IEP: Inferred from expression pattern	21893222	RGD
involved in multicellular organismal response to stress	IEP IEP: Inferred from expression pattern	19113077	RGD
involved in negative regulation of cell adhesion	IDA IDA: Inferred from direct assay	19854170	RGD
involved in ossification	IEP IEP: Inferred from expression pattern	19403161	RGD
involved in osteoclast differentiation	IEP IEP: Inferred from expression pattern	19361364	RGD
involved in positive regulation of cell migration	IMP IMP: Inferred from mutant phenotype	19854170	RGD
involved in response to L-ascorbic acid	IEP IEP: Inferred from expression pattern	19110235	RGD
involved in response to cholesterol	IEP IEP: Inferred from expression pattern	19110235	RGD
involved in response to ethanol	IEP IEP: Inferred from expression pattern	22576626	RGD
involved in response to insulin	IEP IEP: Inferred from expression pattern	20818503	RGD
involved in response to macrophage colony-stimulating factor	IEP IEP: Inferred from expression pattern	7669437	RGD
involved in response to mechanical stimulus	IEP IEP: Inferred from expression pattern	20833686	RGD
involved in response to organic cyclic compound	IEP IEP: Inferred from expression pattern	19264158	RGD
involved in response to zinc ion	IEP IEP: Inferred from expression pattern	19369052	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in extracellular space	IDA IDA: Inferred from direct assay	20003323	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

tartrate-resistant acid phosphatase type 5

TR-AP	acid phosphatase type V
tartrate-resistant acid ATPase	trATPase
type 5 acid phosphatase

Related Agents

Pre-clinical Phase

Bioactive Molecules (5)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-138869	AubipyOMe		≥99.0%	Unkown
HY-124663	CBK289001	Inhibitor	/	Unkown
HY-RS00190	ACP5 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS17325	Acp5 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS23780	Acp5 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Acp5	NCBI	NCBI:54
Mus musculus	Acp5	NCBI	NCBI:11433

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