2. Gene
  3. Igfbp1 - insulin-like growth factor binding protein 1 Gene

Igfbp1 - insulin-like growth factor binding protein 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as IBP1; IGFBA; IGF-BP25

Gene ID: 25685 | Gene type: protein coding

About Igfbp1

Summary

Predicted to enable insulin-like growth factor I binding activity and insulin-like growth factor II binding activity. Involved in several processes, including Insulin Receptor signaling pathway; positive regulation of cell growth; and tissue regeneration. Located in extracellular space. Human ortholog(s) of this gene implicated in diabetic angiopathy. Orthologous to human IGFBP1 (Insulin like growth factor binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Igfbp1 Products(1)

mRNA Protein Name
NM_013144.2 NP_037276.1 insulin-like growth factor-binding protein 1 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in insulin receptor signaling pathway IEP
IEP: Inferred from expression pattern
11784721 RGD
involved in positive regulation of cell growth IEP
IEP: Inferred from expression pattern
1705004 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
7536658 RGD
involved in tissue regeneration IEP
IEP: Inferred from expression pattern
1705004 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
16166214 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

insulin-like growth factor-binding protein 1

IBP-1

IGF-binding protein 1

IGFBP-1

placental protein 12

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06624 IGFBP1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17236 Igfbp1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23689 Igfbp1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Igfbp1 NCBI NCBI:3484
Mus musculus Igfbp1 NCBI NCBI:16006
Macaca mulatta Igfbp1 NCBI NCBI:696994