Slc7a1 - solute carrier family 7 member 1 Gene

Rattus norvegicus

Also known as CAT1; EcoR; Atrc1; Cat-1

Gene ID: 25648 | Gene type: protein coding

About Slc7a1

Summary

Enables L-arginine transmembrane transporter activity. Involved in L-arginine import across plasma membrane; L-arginine transmembrane transport; and regulation of TOR signaling. Located in apical plasma membrane and basal plasma membrane. Orthologous to human SLC7A1 (solute carrier family 7 member 1). [provided by Alliance of Genome Resources, Apr 2022]

Slc7a1 Products(1)

mRNA	Protein	Name
NM_001399982.1	NP_001386911.1	high affinity cationic amino acid transporter 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables L-arginine transmembrane transporter activity	IDA IDA: Inferred from direct assay	17234578	RGD
enables L-arginine transmembrane transporter activity	IMP IMP: Inferred from mutant phenotype	19712052	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in L-arginine import across plasma membrane	IMP IMP: Inferred from mutant phenotype	19712052	RGD
involved in L-arginine transmembrane transport	IMP IMP: Inferred from mutant phenotype	17234578	RGD
involved in regulation of TOR signaling	IMP IMP: Inferred from mutant phenotype	17234578	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in apical plasma membrane	IDA IDA: Inferred from direct assay	19712052	RGD
located in basal plasma membrane	IDA IDA: Inferred from direct assay	19712052	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

high affinity cationic amino acid transporter 1

ERR	Solute carrier family 7 member A1 (amino acid transporter cationic 1)
cationic amino acid transporter, y+ system	cationinc amino acid transporter 1
ecotropic retroviral leukemia receptor	ecotropic retrovirus receptor
solute carrier family 7 (cat

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13323	SLC7A1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS20597	Slc7a1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS27105	Slc7a1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc7a1	NCBI	NCBI:6541

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