2. Gene
  3. Sdc2 - syndecan 2 Gene

Sdc2 - syndecan 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as HSPG

Gene ID: 25615 | Gene type: protein coding

About Sdc2

Summary

Enables PDZ domain binding activity and identical protein binding activity. Involved in several processes, including dendrite morphogenesis; response to caffeine; and response to hypoxia. Located in neuronal cell body. Colocalizes with synapse. Human ortholog(s) of this gene implicated in cleft lip and cleft palate. Orthologous to human SDC2 (syndecan 2). [provided by Alliance of Genome Resources, Apr 2022]

Sdc2 Products(1)

mRNA Protein Name
NM_013082.4 NP_037214.1 syndecan-2 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables PDZ domain binding IPI
IPI: Inferred from physical interaction
9660869 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
26601939 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
11356864 RGD
Biological Process GO Annotation Evidence Reference Source
involved in dendrite morphogenesis IEP
IEP: Inferred from expression pattern
11580899 RGD
involved in regulation of synapse assembly IDA
IDA: Inferred from direct assay
17548511 RGD
involved in regulation of synapse assembly IMP
IMP: Inferred from mutant phenotype
17548511 RGD
involved in regulation of synapse maturation IDA
IDA: Inferred from direct assay
9971750 RGD
involved in regulation of synapse maturation IMP
IMP: Inferred from mutant phenotype
9971750 RGD
involved in response to caffeine IEP
IEP: Inferred from expression pattern
16458123 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
18803305 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
9660869 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
9971750 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
10460248 RGD
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
9660869 RGD
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
9660869 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

syndecan-2

Ryudocan/syndecan 2

SYND2

fibroglycan

heparan sulfate proteoglycan core protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12580 SDC2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18048 Sdc2 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24522 Sdc2 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sdc2 NCBI NCBI:6383
Mus musculus Sdc2 NCBI NCBI:15529