Tle4 - TLE family member 4, transcriptional corepressor Gene

Rattus norvegicus

Also known as Esp2; Grg-4

Gene ID: 25565 | Gene type: protein coding

About Tle4

Summary

Predicted to enable DNA-binding transcription factor binding activity; chromatin binding activity; and transcription corepressor activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within Wnt signaling pathway; cellular response to leukemia inhibitory factor; and negative regulation of transcription by RNA polymerase II. Located in nucleus. Orthologous to human TLE4 (TLE family member 4, transcriptional corepressor). [provided by Alliance of Genome Resources, Apr 2022]

Tle4 Products(2)

mRNA	Protein	Name
NM_001414041.1	NP_001400970.1	transducin-like enhancer protein 4 isoform 1
NM_019141.3	NP_062014.2	transducin-like enhancer protein 4 isoform 2

Protein Preferred Names

Protein Names

transducin-like enhancer protein 4

groucho-related protein 4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
transducin-like enhancer of split 4, E(spl) homolog	transducin-like enhancer of split 4, homolog of Drosophila E(spl)

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14566	TLE4 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21444	Tle4 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS27962	Tle4 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tle4	NCBI	NCBI:7091

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