2. Gene
  3. Il1rl1 - interleukin 1 receptor-like 1 Gene

Il1rl1 - interleukin 1 receptor-like 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as St2; FIT1; Fit-1

Gene ID: 25556 | Gene type: protein coding

About Il1rl1

Summary

Predicted to enable interleukin-33 binding activity and interleukin-33 receptor activity. Involved in several processes, including cellular response to mechanical stimulus; cellular response to peptide; and negative regulation of cell population proliferation. Located in external side of plasma membrane and extracellular space. Biomarker of acute myocardial infarction and Bacterial pneumonia. Human ortholog(s) of this gene implicated in asthma and coronary artery disease. Orthologous to human IL1RL1 (interleukin 1 receptor like 1). [provided by Alliance of Genome Resources, Apr 2022]

Il1rl1 Products(2)

mRNA Protein Name
NM_001127689.1 NP_001121161.1 interleukin-1 receptor-like 1 isoform Fit-1M precursor
NM_013037.1 NP_037169.1 interleukin-1 receptor-like 1 isoform Fit-1S precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to mechanical stimulus IEP
IEP: Inferred from expression pattern
17492053 RGD
involved in cellular response to peptide IEP
IEP: Inferred from expression pattern
18406357 RGD
involved in negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
20014349 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
24265755 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
8131748 RGD
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
8131748 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
20014349 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-1 receptor-like 1

fos-responsive gene 1 protein

Related Agents

Clinical Phase
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P99729 Melrilimab Inhibitor 96.07% Phase 2
Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06725 IL1RL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17312 Il1rl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23767 Il1rl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il1rl1 NCBI NCBI:9173
Macaca fascicularis Il1rl1 NCBI NCBI:102115135
Mus musculus Il1rl1 NCBI NCBI:17082