2. Gene
  3. Cyp7b1 - cytochrome P450 family 7 subfamily B member 1 Gene

Cyp7b1 - cytochrome P450 family 7 subfamily B member 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 25429 | Gene type: protein coding

About Cyp7b1

Summary

Predicted to enable oxysterol 7-alpha-hydroxylase activity. Involved in several processes, including circadian rhythm; memory; and response to cAMP. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 3 and hereditary spastic paraplegia 5A. Orthologous to human CYP7B1 (Cytochrome P450 family 7 subfamily B member 1). [provided by Alliance of Genome Resources, Apr 2022]

Cyp7b1 Products(1)

mRNA Protein Name
NM_019138.1 NP_062011.1 25-hydroxycholesterol 7-alpha-hydroxylase
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in circadian rhythm IDA
IDA: Inferred from direct assay
12759897 RGD
involved in memory IDA
IDA: Inferred from direct assay
17065445 RGD
involved in response to cAMP IEP
IEP: Inferred from expression pattern
12029625 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
12029625 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

25-hydroxycholesterol 7-alpha-hydroxylase

HCT-1

cytochrome P450 7B1

cytochrome P450, family 7, subfamily b, polypeptide 1

cytochrome P450, subfamily 7B, polypeptide 1

hippocampal transcript 1 protein

oxysterol 7-alpha-hydroxylase

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03488 CYP7B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18706 Cyp7b1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25193 Cyp7b1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cyp7b1 NCBI NCBI:9420