2. Gene
  3. Cort - cortistatin Gene

Cort - cortistatin Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 25305 | Gene type: protein coding

About Cort

Summary

Enables neuropeptide hormone activity. Involved in neuropeptide signaling pathway and regulation of circadian sleep/wake cycle, sleep. Predicted to be located in extracellular region. Orthologous to human CORT (cortistatin). [provided by Alliance of Genome Resources, Apr 2022]

Cort Products(1)

mRNA Protein Name
NM_012835.1 NP_036967.1 cortistatin preproprotein
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables neuropeptide hormone activity IDA
IDA: Inferred from direct assay
11817718 RGD
Biological Process GO Annotation Evidence Reference Source
involved in neuropeptide signaling pathway IDA
IDA: Inferred from direct assay
11817718 RGD
involved in regulation of circadian sleep/wake cycle, sleep IDA
IDA: Inferred from direct assay
8622767 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cortistatin

Preprocortistatin

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-117880 Exicorilant Antagonist 99.48% Phase 2
HY-15710 Cort108297 Antagonist 99.80% Phase 2
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-109042 Relacorilant Antagonist 99.12% Yes
HY-132811 Dazucorilant Modulator 98.91% Unkown
HY-117965 Miricorilant / Unkown
HY-RS03054 CORT Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS16810 Cort Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23250 Cort Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cort NCBI NCBI:1325
Macaca fascicularis Cort NCBI NCBI:102138191
Mus musculus Cort NCBI NCBI:12854