Gdf6 - growth differentiation factor 6 Gene

Also known as gdf16; BMP-13

About Gdf6

Summary

Predicted to enable cytokine activity and identical protein binding activity. Predicted to be involved in several processes, including positive regulation of chondrocyte differentiation; positive regulation of signal transduction; and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to act upstream of or within with a positive effect on cell migration involved in metanephros development. Predicted to act upstream of or within positive regulation of neuron differentiation. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including Klippel-Feil syndrome 1; Leber congenital amaurosis 17; cleft lip; isolated microphthalmia 4; and multiple synostoses syndrome. Orthologous to human GDF6 (Growth Differentiation Factor 6). [provided by Alliance of Genome Resources, Apr 2022]