2. Gene
  3. Mfge8 - milk fat globule EGF and factor V/VIII domain containing Gene

Mfge8 - milk fat globule EGF and factor V/VIII domain containing Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as AGS; MFGME8; OAcGD3S; MFGMP-E8

Gene ID: 25277 | Gene type: protein coding

About Mfge8

Summary

Predicted to enable Integrin binding activity; phosphatidylethanolamine binding activity; and phosphatidylserine binding activity. Involved in positive regulation of cell population proliferation and response to estrogen. Predicted to be located in external side of plasma membrane and extracellular space. Predicted to be extrinsic component of plasma membrane. Human ortholog(s) of this gene implicated in temporal arteritis. Orthologous to human MFGE8 (milk fat globule EGF and factor V/VIII domain containing). [provided by Alliance of Genome Resources, Apr 2022]

Mfge8 Products(2)

mRNA Protein Name
NM_001040186.2 NP_001035276.1 lactadherin isoform 1 precursor
NM_012811.3 NP_036943.1 lactadherin isoform 2 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of cell population proliferation IEP
IEP: Inferred from expression pattern
11085522 RGD
involved in response to estrogen IEP
IEP: Inferred from expression pattern
12801995 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lactadherin

MFG-E8

MFGM

O-acetyl GD3 ganglioside synthase

O-acetyl disialoganglioside synthase

O-acetyltransferase Milk fat glolbule membrane protein

O-acetyltransferase milk fat globule membrane protein

SED1

milk fat globule-EGF factor 8 protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08381 MFGE8 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19023 Mfge8 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25512 Mfge8 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mfge8 NCBI NCBI:4240