2. Gene
  3. Gamt - guanidinoacetate N-methyltransferase Gene

Gamt - guanidinoacetate N-methyltransferase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as GMT

Gene ID: 25257 | Gene type: protein coding

About Gamt

Summary

Enables guanidinoacetate N-methyltransferase activity and identical protein binding activity. Involved in S-adenosylmethionine metabolic process; carboxylic acid metabolic process; and embryonic liver development. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and guanidinoacetate methyltransferase deficiency. Orthologous to human GAMT (guanidinoacetate N-methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Gamt Products(2)

mRNA Protein Name
NM_001402213.1 NP_001389142.1 guanidinoacetate N-methyltransferase isoform 2
NM_012793.3 NP_036925.2 guanidinoacetate N-methyltransferase isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables S-adenosylmethionine-dependent methyltransferase activity IDA
IDA: Inferred from direct assay
15533043 RGD
enables guanidinoacetate N-methyltransferase activity IDA
IDA: Inferred from direct assay
12069495 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
12079381 RGD
Biological Process GO Annotation Evidence Reference Source
involved in S-adenosylhomocysteine metabolic process IDA
IDA: Inferred from direct assay
15533043 RGD
involved in S-adenosylmethionine metabolic process IDA
IDA: Inferred from direct assay
15533043 RGD
involved in creatine biosynthetic process IDA
IDA: Inferred from direct assay
15533043 RGD
involved in embryonic liver development IEP
IEP: Inferred from expression pattern
15918910 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanidinoacetate N-methyltransferase

guanidinoacetate methyltransferase

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05268 GAMT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18478 Gamt Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24959 Gamt Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gamt NCBI NCBI:2593