Ccnb1 - cyclin B1 Gene

Rattus norvegicus

Gene ID: 25203 | Gene type: protein coding

About Ccnb1

Summary

Enables protein kinase binding activity. Involved in several processes, including cellular response to iron(III) ion; gamete generation; and regulation of protein phosphorylation. Located in cytoplasm and nucleus. Biomarker of visual epilepsy. Human ortholog(s) of this gene implicated in breast Cancer and prostate Cancer. Orthologous to human CCNB1 (cyclin B1). [provided by Alliance of Genome Resources, Apr 2022]

Ccnb1 Products(1)

mRNA	Protein	Name
NM_171991.3	NP_741988.1	G2/mitotic-specific cyclin-B1

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein kinase binding	IPI IPI: Inferred from physical interaction	19821535	RGD
enables protein-containing complex binding	IPI IPI: Inferred from physical interaction	14512566	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to fatty acid	IEP IEP: Inferred from expression pattern	14674679	RGD
involved in cellular response to hypoxia	IEP IEP: Inferred from expression pattern	12374461	RGD
involved in cellular response to iron(III) ion	IEP IEP: Inferred from expression pattern	18254965	RGD
involved in cellular response to organic cyclic compound	IEP IEP: Inferred from expression pattern	19298190	RGD
involved in digestive tract development	IEP IEP: Inferred from expression pattern	17692466	RGD
involved in negative regulation of gene expression	IMP IMP: Inferred from mutant phenotype	15291744	RGD
involved in negative regulation of protein phosphorylation	IMP IMP: Inferred from mutant phenotype	15291744	RGD
involved in oocyte maturation	IMP IMP: Inferred from mutant phenotype	15291744	RGD
involved in positive regulation of cardiac muscle cell proliferation	IDA IDA: Inferred from direct assay	15253691	RGD
involved in positive regulation of mRNA 3'-end processing	IMP IMP: Inferred from mutant phenotype	15291744	RGD
involved in positive regulation of protein kinase activity	IMP IMP: Inferred from mutant phenotype	15291744	RGD
involved in protein-containing complex assembly	IDA IDA: Inferred from direct assay	19136513	RGD
involved in regulation of chromosome condensation	IMP IMP: Inferred from mutant phenotype	15291744	RGD
involved in response to DDT	IEP IEP: Inferred from expression pattern	17984292	RGD
involved in response to mechanical stimulus	IEP IEP: Inferred from expression pattern	15040886	RGD
involved in response to toxic substance	IEP IEP: Inferred from expression pattern	16919876	RGD
involved in response to xenobiotic stimulus	IEP IEP: Inferred from expression pattern	16426843	RGD
involved in spermatogenesis	IEP IEP: Inferred from expression pattern	11139145	RGD
involved in tissue regeneration	IEP IEP: Inferred from expression pattern	8123599	RGD
involved in ventricular cardiac muscle cell development	IEP IEP: Inferred from expression pattern	15253691	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

G2/mitotic-specific cyclin-B1

Related Agents

Pre-clinical Phase

Bioactive Molecules (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-114779	N9-Isopropylolomoucine	Inhibitor	99.34%	Unkown
HY-RS02118	CCNB1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-162895	NL13		/	Unkown
HY-RS02119	CCNB1IP1 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS17545	Ccnb1 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS24004	Ccnb1 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ccnb1	NCBI	NCBI:891

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