2. Gene
  3. Xrcc6 - X-ray repair cross complementing 6 Gene

Xrcc6 - X-ray repair cross complementing 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Ku70; G22p1; Kup70

Gene ID: 25019 | Gene type: protein coding

About Xrcc6

Summary

Contributes to double-stranded DNA binding activity. Involved in brain development; cellular hyperosmotic salinity response; and cellular response to X-ray. Located in cytoplasm and nucleolus. Part of protein-containing complex. Orthologous to human XRCC6 (X-ray repair cross complementing 6). [provided by Alliance of Genome Resources, Apr 2022]

Xrcc6 Products(1)

mRNA Protein Name
NM_139080.2 NP_620780.2 X-ray repair cross-complementing protein 6
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
contributes to double-stranded DNA binding IDA
IDA: Inferred from direct assay
14576192 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
14576192 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cellular hyperosmotic salinity response IDA
IDA: Inferred from direct assay
11175667 RGD
involved in cellular response to X-ray IDA
IDA: Inferred from direct assay
11175667 RGD
Cellular Component GO Annotation Evidence Reference Source
part of protein-containing complex IDA
IDA: Inferred from direct assay
14576192 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

X-ray repair cross-complementing protein 6

Ku70 DNA-binding component of DNA-dependent proteinkinase complex (thyroid autoantigen 70 kDa)

X-ray repair complementing defective repair in Chinese hamster cells 6

thyroid autoantigen

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15901 XRCC6 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS01190 ATP23 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19756 Xrcc6 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21489 Atp23 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26253 Xrcc6 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS28007 Atp23 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Xrcc6 NCBI NCBI:2547