Thrb - thyroid hormone receptor beta Gene

Rattus norvegicus

Also known as ERBA2; Nr1a2; T3rec; TRbeta; RATT3REC; c-erbA-2; C-erba-beta

Gene ID: 24831 | Gene type: protein coding

About Thrb

Summary

Enables double-stranded DNA binding activity; identical protein binding activity; and nuclear receptor activity. Involved in several processes, including positive regulation of chondrocyte differentiation; positive regulation of ossification; and regulation of lipid metabolic process. Predicted to be located in nuclear body. Used to study breast Cancer. Human ortholog(s) of this gene implicated in several diseases, including cervix uteri carcinoma in situ; prostate cancer; renal cell carcinoma; selective pituitary thyroid hormone resistance; and thyroid hormone resistance syndrome. Orthologous to human THRB (Thyroid Hormone Receptor beta). [provided by Alliance of Genome Resources, Apr 2022]

Thrb Products(2)

mRNA	Protein	Name
NM_001270854.1	NP_001257783.1	thyroid hormone receptor beta isoform 2
NM_012672.3	NP_036804.2	thyroid hormone receptor beta isoform 1

Protein Preferred Names

Protein Names

thyroid hormone receptor beta

TRbeta2Delta	nuclear receptor subfamily 1 group A member 2
thyroid hormone receptor beta 3	thyroid hormone receptor beta2delta
thyroid hormone receptor, beta (avian erythroblastic leukemia viral (v-erb-a) oncogene homolog 2)

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14501	THRB Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS20346	Thrb Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS26855	Thrb Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Thrb	NCBI	NCBI:7068

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