PRPS2 - Prps2 phosphoribosyl pyrophosphate synthetase 2 Gene

Rattus norvegicus

Gene ID: 24689 | Gene type: protein coding

About PRPS2

Summary

Enables several functions, including magnesium ion binding activity; purine ribonucleotide binding activity; and ribose phosphate diphosphokinase activity. Involved in 5-phosphoribose 1-diphosphate biosynthetic process; AMP biosynthetic process; and animal organ regeneration. Part of ribose phosphate diphosphokinase complex. Orthologous to human PRPS2 (phosphoribosyl pyrophosphate synthetase 2). [provided by Alliance of Genome Resources, Apr 2022]

PRPS2 Products(1)

mRNA	Protein	Name
NM_012634.2	NP_036766.1	ribose-phosphate pyrophosphokinase 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables ADP binding	IDA IDA: Inferred from direct assay	1651917	RGD
enables AMP binding	IDA IDA: Inferred from direct assay	1651917	RGD
enables ATP binding	IDA IDA: Inferred from direct assay	1651917	RGD
enables GDP binding	IDA IDA: Inferred from direct assay	1651917	RGD
enables carbohydrate binding	IDA IDA: Inferred from direct assay	1651917	RGD
enables magnesium ion binding	IDA IDA: Inferred from direct assay	1651917	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	9366267	RGD
enables ribose phosphate diphosphokinase activity	IDA IDA: Inferred from direct assay	1651917	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in 5-phosphoribose 1-diphosphate biosynthetic process	IDA IDA: Inferred from direct assay	9366267	RGD
involved in AMP biosynthetic process	IDA IDA: Inferred from direct assay	2546925	RGD
involved in animal organ regeneration	IEP IEP: Inferred from expression pattern	2822704	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
part of protein-containing complex	IDA IDA: Inferred from direct assay	2546925	RGD
part of ribose phosphate diphosphokinase complex	IDA IDA: Inferred from direct assay	2546925	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

ribose-phosphate pyrophosphokinase 2

PRS-II	Phophoribosylpyrophosphate synthetase, subunit II
phosphoribosyl pyrophosphate synthase II	phosphoribosyl pyrophosphate synthetase II
ribose-phosphate pyrophosphokinase 2-like

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11220	PRPS2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS18836	Prps2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS25328	Prps2 Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	PRPS2	NCBI	NCBI:5634

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