2. Gene
  3. Tnfsf10 - TNF superfamily member 10 Gene

Tnfsf10 - TNF superfamily member 10 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Trail; Tnlg6a

Gene ID: 246775 | Gene type: protein coding

About Tnfsf10

Summary

Predicted to enable several functions, including TRAIL binding activity; identical protein binding activity; and zinc ion binding activity. Involved in male gonad development; positive regulation of apoptotic process; and response to Insulin. Predicted to be located in extracellular space. Predicted to be integral component of membrane. Biomarker of osteoarthritis and polycystic ovary syndrome. Human ortholog(s) of this gene implicated in arteriosclerosis and small cell carcinoma. Orthologous to human TNFSF10 (TNF Superfamily member 10). [provided by Alliance of Genome Resources, Apr 2022]

Tnfsf10 Products(1)

mRNA Protein Name
NM_145681.2 NP_663714.2 tumor necrosis factor ligand superfamily member 10
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in male gonad development IEP
IEP: Inferred from expression pattern
12021051 RGD
involved in positive regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
19385008 RGD
involved in response to insulin IEP
IEP: Inferred from expression pattern
17352408 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor necrosis factor ligand superfamily member 10

tumor necrosis factor (ligand) superfamily, member 10

tumor necrosis factor ligand 6a

tumor necrosis factor superfamily member 10

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14818 TNFSF10 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17568 Tnfsf10 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24028 Tnfsf10 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tnfsf10 NCBI NCBI:8743
Mus musculus Tnfsf10 NCBI NCBI:22035
Macaca mulatta Tnfsf10 NCBI NCBI:694451