Inha - inhibin subunit alpha Gene

Rattus norvegicus

Gene ID: 24504 | Gene type: protein coding

About Inha

Summary

Enables inhibin binding activity. Involved in male gonad development; negative regulation of follicle-stimulating hormone secretion; and ovarian follicle development. Located in several cellular components, including neuronal cell body; photoreceptor inner segment; and photoreceptor outer segment. Part of Inhibin A complex and Inhibin B complex. Biomarker of Leydig cell tumor. Human ortholog(s) of this gene implicated in prostate carcinoma. Orthologous to human INHA (inhibin subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Inha Products(1)

mRNA	Protein	Name
NM_012590.2	NP_036722.1	inhibin alpha chain precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables inhibin binding	IPI IPI: Inferred from physical interaction	8994390	RGD
enables protein-containing complex binding	IDA IDA: Inferred from direct assay	8994390	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in male gonad development	IMP IMP: Inferred from mutant phenotype	9019274	RGD
involved in negative regulation of follicle-stimulating hormone secretion	IMP IMP: Inferred from mutant phenotype	2500324	RGD
involved in ovarian follicle development	IMP IMP: Inferred from mutant phenotype	18243599	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in extracellular space	IDA IDA: Inferred from direct assay	8014597	RGD
part of inhibin A complex	IDA IDA: Inferred from direct assay	8994390	RGD
part of inhibin B complex	IDA IDA: Inferred from direct assay	17636211	RGD
located in neuronal cell body	IDA IDA: Inferred from direct assay	10201810	RGD
located in photoreceptor inner segment	IDA IDA: Inferred from direct assay	7596220	RGD
located in photoreceptor outer segment	IDA IDA: Inferred from direct assay	7596220	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

inhibin alpha chain

inhibin alpha subunit

Related Agents

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-B0306	Prothionamide	Inhibitor	99.87%	Unkown

Pre-clinical Phase

Bioactive Molecules (19)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-122643	NITD-916	Inhibitor	99.83%	Unkown
HY-111402	Pyridomycin	Inhibitor	/	Unkown
HY-147047	InhA-IN-2	Inhibitor	/	Unkown
HY-150588	InhA-IN-3	Inhibitor	/	Unkown
HY-150589	InhA-IN-4	Inhibitor	/	Unkown
HY-159565	VEGFR-2/InhA-IN-1	Inhibitor	/	Unkown
HY-160644	8PC		/	Unkown
HY-160648	InhA-IN-6	Inhibitor	/	Unkown
HY-160653	JPL	Inhibitor	/	Unkown
HY-160678	InhA-IN-7	Inhibitor	/	Unkown
HY-162033	PAT1inh-A0030	Inhibitor	/	Unkown
HY-169104	InhA-IN-8	Inhibitor	/	Unkown
HY-B0306S	Prothionamide-d5	Inhibitor	/	Unkown
HY-RS06812	INHA Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-120884	InhA-IN-5	Inhibitor	/	Unkown
HY-168946	InhA-IN-9	Inhibitor	/	Unkown
HY-169635	Mycobacterium Tuberculosis-IN-6	Inhibitor	/	Unkown
HY-RS19905	Inha Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS26406	Inha Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Inha	NCBI	NCBI:3623

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