2. Gene
  3. Iapp - islet amyloid polypeptide Gene

Iapp - islet amyloid polypeptide Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 24476 | Gene type: protein coding

About Iapp

Summary

Predicted to enable identical protein binding activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; Amylin Receptor signaling pathway; and eating behavior. Predicted to be located in inclusion body and neuronal cell body. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus and type 2 diabetes mellitus. Orthologous to human IAPP (islet amyloid polypeptide). [provided by Alliance of Genome Resources, Apr 2022]

Iapp Products(1)

mRNA Protein Name
NM_012586.3 NP_036718.1 islet amyloid polypeptide preproprotein
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IGI
IGI: Inferred from genetic interaction
22500019 RGD
involved in amylin receptor signaling pathway IGI
IGI: Inferred from genetic interaction
22500019 RGD
involved in eating behavior IMP
IMP: Inferred from mutant phenotype
15130879 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

islet amyloid polypeptide

DAP

amylin

diabetes-associated peptide

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P1871A Amylin (IAPP), feline TFA 98.75% Unkown
HY-P1871 Amylin (IAPP), feline / Unkown
HY-P3926 Amylin (8-37) (human) / Unkown
HY-P4767 Amylin (1-13) (human) Ligand / Unkown
HY-RS06506 IAPP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17689 Iapp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24151 Iapp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Iapp NCBI NCBI:3375