2. Gene
  3. Gad2 - glutamate decarboxylase 2 Gene

Gad2 - glutamate decarboxylase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as gad65

Gene ID: 24380 | Gene type: protein coding

About Gad2

Summary

Enables glutamate binding activity; glutamate decarboxylase activity; and pyridoxal phosphate binding activity. Involved in glutamate decarboxylation to succinate and response to xenobiotic stimulus. Located in several cellular components, including inhibitory synapse; perinuclear region of cytoplasm; and synaptic vesicle membrane. Is anchored component of membrane. Human ortholog(s) of this gene implicated in gestational diabetes; schizophrenia; and type 1 diabetes mellitus. Orthologous to human GAD2 (glutamate decarboxylase 2). [provided by Alliance of Genome Resources, Apr 2022]

Gad2 Products(1)

mRNA Protein Name
NM_012563.2 NP_036695.1 glutamate decarboxylase 2
Protein Preferred Names Protein Names

glutamate decarboxylase 2

65 kDa glutamic acid decarboxylase

GAD-65

Glutamate decarboxylase 2 (islet)

glutamic acid decarboxylase 2

glutamic acid decarboxylase 65

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS05228 GAD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18758 Gad2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25245 Gad2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gad2 NCBI NCBI:2572
Mus musculus Gad2 NCBI NCBI:14417