2. Gene
  3. Fgb - fibrinogen beta chain Gene

Fgb - fibrinogen beta chain Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Ab1-181; Ab1-216; Ac1-581

Gene ID: 24366 | Gene type: protein coding

About Fgb

Summary

Predicted to enable chaperone binding activity; signaling receptor binding activity; and structural molecule activity. Predicted to contribute to cell adhesion molecule binding activity. Involved in cellular response to interleukin-1 and cellular response to Leptin stimulus. Located in blood microparticle and cytoplasm. Biomarker of pancreatitis and pulmonary embolism. Human ortholog(s) of this gene implicated in cardiovascular system disease (multiple); congenital afibrinogenemia; and end stage renal disease. Orthologous to human FGB (fibrinogen beta chain). [provided by Alliance of Genome Resources, Apr 2022]

Fgb Products(1)

mRNA Protein Name
NM_020071.2 NP_064456.2 fibrinogen beta chain precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to interleukin-1 IEP
IEP: Inferred from expression pattern
17521427 RGD
involved in cellular response to leptin stimulus IEP
IEP: Inferred from expression pattern
17521427 RGD
Cellular Component GO Annotation Evidence Reference Source
located in blood microparticle IDA
IDA: Inferred from direct assay
22014850 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibrinogen beta chain

beta-fibrinogen

fibrinogen, B beta polypeptide

fibrinogen, beta polypeptide

liver regeneration-related protein LRRG036/LRRG043/LRRG189

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS19861 Fgb Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS04879 FGB Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26361 Fgb Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgb NCBI NCBI:2244