2. Gene
  3. Ppm1k - protein phosphatase 1K (PP2C domain containing) Gene

Ppm1k - protein phosphatase 1K (PP2C domain containing) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as PP2Cm; PP2C-kappa; 2900063A19Rik; A930026L03Rik

Gene ID: 243382 | Gene type: protein coding

About Ppm1k

Summary

Predicted to enable metal ion binding activity; protein serine Phosphatase activity; and protein threonine Phosphatase activity. Located in mitochondrion. Is expressed in several structures, including diaphragm; gut; heart; liver; and spleen. Used to study maple syrup urine disease. Human ortholog(s) of this gene implicated in maple syrup urine disease. Orthologous to human PPM1K (protein Phosphatase, Mg2+/Mn2+ dependent 1K). [provided by Alliance of Genome Resources, Apr 2022]

Ppm1k Products(1)

mRNA Protein Name
NM_175523.5 NP_780732.1 protein phosphatase 1K, mitochondrial precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in regulation of mitochondrial membrane permeability involved in apoptotic process IMP
IMP: Inferred from mutant phenotype
17374715 MGI
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrial matrix IDA
IDA: Inferred from direct assay
17374715 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein phosphatase 1K, mitochondrial

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10968 PPM1K Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21696 Ppm1k Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppm1k NCBI NCBI:152926