Elfn1 - leucine rich repeat and fibronectin type III, extracellular 1 Gene

Mus musculus

Also known as Ppp1r28; A930017N06Rik

Gene ID: 243312 | Gene type: protein coding

About Elfn1

Summary

Predicted to enable protein Phosphatase Inhibitor activity. Involved in synapse organization. Located in dendrite and excitatory synapse. Is expressed in several structures, including adrenal gland; eye; gut; male reproductive gland or organ; and nervous system. Orthologous to human ELFN1 (extracellular leucine rich repeat and fibronectin type III domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]

Elfn1 Products(2)

mRNA	Protein	Name
NM_001384186.1	NP_001371115.1	protein ELFN1 precursor
NM_175522.4	NP_780731.1	protein ELFN1 precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32879010	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within chemical synaptic transmission	IGI IGI: Inferred from genetic interaction	32879010	MGI
acts upstream of or within establishment of protein localization	IDA IDA: Inferred from direct assay	32879010	MGI
acts upstream of or within synapse assembly	IMP IMP: Inferred from mutant phenotype	36179691	MGI
involved in synapse organization	IMP IMP: Inferred from mutant phenotype	23042292	MGI
involved in synaptic membrane adhesion	IDA IDA: Inferred from direct assay	25047565	MGI
involved in synaptic membrane adhesion	IEP IEP: Inferred from expression pattern	25047565	MGI
involved in synaptic membrane adhesion	IMP IMP: Inferred from mutant phenotype	25047565	MGI
acts upstream of or within synaptic signaling	IMP IMP: Inferred from mutant phenotype	36179691	MGI
acts upstream of or within visual perception	IMP IMP: Inferred from mutant phenotype	36179691	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in axon terminus	IDA IDA: Inferred from direct assay	36179691	MGI
located in dendrite	IDA IDA: Inferred from direct assay	23042292	MGI
located in excitatory synapse	IDA IDA: Inferred from direct assay	23042292	MGI
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	25047565	MGI
is active in glutamatergic synapse	IEP IEP: Inferred from expression pattern	25047565	MGI
is active in glutamatergic synapse	IMP IMP: Inferred from mutant phenotype	25047565	MGI
is active in neuron projection terminus	IDA IDA: Inferred from direct assay	32879010	MGI
is active in postsynaptic density membrane	IDA IDA: Inferred from direct assay	25047565	MGI
is active in postsynaptic density membrane	IEP IEP: Inferred from expression pattern	25047565	MGI
is active in postsynaptic density membrane	IMP IMP: Inferred from mutant phenotype	25047565	MGI
is active in synapse	IDA IDA: Inferred from direct assay	36179691	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

protein ELFN1

extracellular leucine-rich repeat and fibronectin type-III domain-containing protein 1

protein phosphatase 1 regulatory subunit 28

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04303	ELFN1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS22483	Elfn1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Elfn1	NCBI	NCBI:392617

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