Cyp1a2 - cytochrome P450, family 1, subfamily a, polypeptide 2 Gene

Rattus norvegicus

Also known as CYPD45; P-450d; RATCYPD45

Gene ID: 24297 | Gene type: protein coding

About Cyp1a2

Summary

Enables oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen. Involved in several processes, including cellular response to copper ion; response to estradiol; and response to lipopolysaccharide. Located in intracellular membrane-bounded organelle. Biomarker of mental depression. Human ortholog(s) of this gene implicated in breast cancer; chronic obstructive pulmonary disease; endometrial cancer; and porphyria cutanea tarda. Orthologous to human CYP1A2 (Cytochrome P450 family 1 subfamily A member 2). [provided by Alliance of Genome Resources, Apr 2022]

Cyp1a2 Products(1)

mRNA	Protein	Name
NM_012541.3	NP_036673.3	cytochrome P450 1A2

Protein Preferred Names

Protein Names

cytochrome P450 1A2

CYPIA2	Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d)
P-448	P450-D
cholesterol 25-hydroxylase	cytochrome P-448
cytochrome P-450d	cytochrome P450, 1a2
cytochrome P450, subfamily I (aromatic compound-inducible), mem

Related Agents

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-132845	Utreloxastat	Inhibitor	99.69%	Phase 2

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-170846	FGFRs-IN-1	Inhibitor	/	Unkown
HY-174417	NNRT-IN-10	Inhibitor	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cyp1a2	NCBI	NCBI:1544

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