Slc1a7 - solute carrier family 1 (glutamate transporter), member 7 Gene

Mus musculus

Also known as Eaat5; A930031E15Rik

Gene ID: 242607 | Gene type: protein coding

About Slc1a7

Summary

Enables L-glutamate transmembrane transporter activity. Acts upstream of or within L-glutamate transmembrane transport. Located in plasma membrane. Is integral component of presynaptic membrane. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane. Is expressed in several structures, including cerebellum; mesenchyme of metanephros; and retina nuclear layer. Orthologous to human SLC1A7 (solute carrier family 1 member 7). [provided by Alliance of Genome Resources, Apr 2022]

Slc1a7 Products(1)

mRNA	Protein	Name
NM_146255.3	NP_666367.3	excitatory amino acid transporter 5

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables L-glutamate transmembrane transporter activity	IDA IDA: Inferred from direct assay	24307171	MGI
enables extracellularly glutamate-gated chloride channel activity	IDA IDA: Inferred from direct assay	16973698	MGI
enables glutamate:sodium symporter activity	IDA IDA: Inferred from direct assay	16973698	MGI
enables monoatomic anion transmembrane transporter activity	IDA IDA: Inferred from direct assay	24307171	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within L-glutamate transmembrane transport	IDA IDA: Inferred from direct assay	24307171	MGI
involved in L-glutamate transmembrane transport	IDA IDA: Inferred from direct assay	16973698	MGI
involved in chloride transmembrane transport	IDA IDA: Inferred from direct assay	32233906	MGI
acts upstream of or within monoatomic anion transmembrane transport	IDA IDA: Inferred from direct assay	24307171	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in axon terminus	IDA IDA: Inferred from direct assay	16973698	MGI
is active in glutamatergic synapse	IDA IDA: Inferred from direct assay	23049999	MGI
located in photoreceptor cell terminal bouton	IDA IDA: Inferred from direct assay	16973698	MGI
located in plasma membrane	IDA IDA: Inferred from direct assay	24307171	MGI
is active in postsynaptic membrane	IDA IDA: Inferred from direct assay	23049999	MGI
is active in presynaptic membrane	IDA IDA: Inferred from direct assay	23049999	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

excitatory amino acid transporter 5

solute carrier family 1 member 7

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13058	SLC1A7 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21935	Slc1a7 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Slc1a7	NCBI	NCBI:6512

Name
Email *

	Sorry, but the email address you supplied was invalid.