2. Gene
  3. Adh1 - alcohol dehydrogenase 1C (class I), gamma polypeptide Gene

Adh1 - alcohol dehydrogenase 1C (class I), gamma polypeptide Gene

  • Gene
  • Protein
  • Agent
Rattus norvegicus

Also known as Adh; Adh1a; Adh1c

Gene ID: 24172 | Gene type: protein coding

About Adh1

Summary

Enables NAD binding activity; ethanol binding activity; and oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Involved in several processes, including acetaldehyde biosynthetic process; ethanol oxidation; and response to progesterone. Located in cytosol. Human ortholog(s) of this gene implicated in alcohol use disorder; late onset Parkinson's disease; and pancreatic Cancer. Orthologous to human ADH1A (alcohol dehydrogenase 1A (class I), alpha polypeptide); ADH1B (alcohol dehydrogenase 1B (class I), beta polypeptide); and ADH1C (alcohol dehydrogenase 1C (class I), gamma polypeptide). [provided by Alliance of Genome Resources, Apr 2022]

Adh1 Products(1)

mRNA Protein Name
NM_019286.4 NP_062159.3 alcohol dehydrogenase 1
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables alcohol dehydrogenase (NAD+) activity IDA
IDA: Inferred from direct assay
1558299 RGD
enables all-trans-retinol dehydrogenase (NAD+) activity IDA
IDA: Inferred from direct assay
2940107 RGD
enables organic cyclic compound binding IPI
IPI: Inferred from physical interaction
16385241 RGD
Biological Process GO Annotation Evidence Reference Source
involved in animal organ regeneration IEP
IEP: Inferred from expression pattern
17126819 RGD
involved in lipid metabolic process IDA
IDA: Inferred from direct assay
10094961 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
23413777 RGD
involved in response to progesterone IEP
IEP: Inferred from expression pattern
18219182 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alcohol dehydrogenase 1

alcohol dehydrogenase (class I), alpha polypeptide

alcohol dehydrogenase 1 (class I)

alcohol dehydrogenase 1, complex

alcohol dehydrogenase A subunit

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-13541 ADH-1 Antagonist 99.93% Phase 2
HY-13541A ADH-1 trifluoroacetate Antagonist 99.74% Phase 2
Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-122297 H-​Arg-​Phe-​OH / Unkown
HY-RS00366 ADH1A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00367 ADH1B Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS00368 ADH1C Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25084 Adh4 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS27366 Adh1c Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown