2. Gene
  3. Usp18 - ubiquitin specific peptidase 18 Gene

Usp18 - ubiquitin specific peptidase 18 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as UBP43; Ubp15; 1110058H21Rik

Gene ID: 24110 | Gene type: protein coding

About Usp18

Summary

Enables ISG15-specific protease activity. Acts upstream of or within response to bacterium and response to stilbenoid. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be active in cytosol and nucleus. Is expressed in axial skeleton; lung; and mandible. Orthologous to several human genes including USP18 (ubiquitin specific peptidase 18). [provided by Alliance of Genome Resources, Apr 2022]

Usp18 Products(1)

mRNA Protein Name
NM_011909.2 NP_036039.2 ubl carboxyl-terminal hydrolase 18
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables ISG15-specific peptidase activity IMP
IMP: Inferred from mutant phenotype
16139798 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
24533902 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
involved in response to stilbenoid IEP
IEP: Inferred from expression pattern
17086191 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubl carboxyl-terminal hydrolase 18

43 kDa ISG15-specific protease

ISG15-specific-processing protease

ubiquitin specific protease 15

ubiquitin specific protease 18

ubl thioesterase 18

ubl thiolesterase 18

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-111458 GSK2643943A Inhibitor 98.79% Unkown
HY-172969 ZHAWOC8655 Inhibitor / Unkown
HY-RS15528 USP18 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17777 Usp18 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24244 Usp18 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp18 NCBI NCBI:11274