Dmrt3 - doublesex and mab-3 related transcription factor 3 Gene

Mus musculus

Gene ID: 240590 | Gene type: protein coding

About Dmrt3

Summary

Enables sequence-specific DNA binding activity. Acts upstream of or within several processes, including adult walking behavior; transmission of nerve impulse; and ventral spinal cord interneuron specification. Located in nucleus. Is expressed in several structures, including adrenal gland; alimentary system; central nervous system; genitourinary system; and nose. Orthologous to human DMRT3 (doublesex and mab-3 related transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Dmrt3 Products(1)

mRNA	Protein	Name
NM_177360.3	NP_796334.2	doublesex- and mab-3-related transcription factor 3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	17605809	MGI
enables sequence-specific DNA binding	IDA IDA: Inferred from direct assay	17605809	MGI

Biological Process GO Annotation	Evidence	Reference	Source
acts upstream of or within adult walking behavior	IMP IMP: Inferred from mutant phenotype	22932389	MGI
acts upstream of or within male sex differentiation	IMP IMP: Inferred from mutant phenotype	17803355	MGI
acts upstream of or within regulation of odontogenesis of dentin-containing tooth	IMP IMP: Inferred from mutant phenotype	17803355	MGI
acts upstream of or within transmission of nerve impulse	IMP IMP: Inferred from mutant phenotype	22932389	MGI
acts upstream of or within ventral spinal cord interneuron specification	IMP IMP: Inferred from mutant phenotype	22932389	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in nucleus	IDA IDA: Inferred from direct assay	23056351	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

doublesex- and mab-3-related transcription factor 3

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS03830	DMRT3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS22471	Dmrt3 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Dmrt3	NCBI	NCBI:58524

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