2. Gene
  3. Sh3bp5 - SH3-domain binding protein 5 (BTK-associated) Gene

Sh3bp5 - SH3-domain binding protein 5 (BTK-associated) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Sab; SH3BP-5

Gene ID: 24056 | Gene type: protein coding

About Sh3bp5

Summary

Predicted to enable guanyl-nucleotide exchange factor activity and protein kinase inhibitor activity. Involved in negative regulation of protein kinase activity. Predicted to be located in cytoplasmic vesicle membrane; mitochondrion; and nuclear body. Predicted to be active in cytoplasm. Orthologous to human SH3BP5 (SH3 domain binding protein 5). [provided by Alliance of Genome Resources, Apr 2022]

Sh3bp5 Products(6)

mRNA Protein Name
NM_001347585.2 NP_001334514.1 SH3 domain-binding protein 5 isoform 2
NM_001404586.1 NP_001391515.1 SH3 domain-binding protein 5 isoform 3
NM_001404587.1 NP_001391516.1 SH3 domain-binding protein 5 isoform 4
NM_001404588.1 NP_001391517.1 SH3 domain-binding protein 5 isoform 5
NM_001404589.1 NP_001391518.1 SH3 domain-binding protein 5 isoform 6
NM_011894.4 NP_036024.2 SH3 domain-binding protein 5 isoform 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in negative regulation of protein kinase activity IDA
IDA: Inferred from direct assay
10339589 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SH3 domain-binding protein 5

SH3 domain-binding protein that preferentially associates with BTK

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12833 SH3BP5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21931 Sh3bp5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sh3bp5 NCBI NCBI:9467