2. Gene
  3. Mtr - 5-methyltetrahydrofolate-homocysteine methyltransferase Gene

Mtr - 5-methyltetrahydrofolate-homocysteine methyltransferase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as MS; D830038K18Rik

Gene ID: 238505 | Gene type: protein coding

About Mtr

Summary

Enables methionine synthase activity. Acts upstream of or within methionine biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including eye; genitourinary system; integumental system; limb; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autistic disorder; hematologic Cancer (multiple); hyperhomocysteinemia; and methylmalonic aciduria and homocystinuria type cblG. Orthologous to human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Mtr Products(1)

mRNA Protein Name
NM_001081128.3 NP_001074597.1 methionine synthase
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables methionine synthase activity IMP
IMP: Inferred from mutant phenotype
11158293 MGI
Biological Process GO Annotation Evidence Reference Source
involved in cobalamin metabolic process IMP
IMP: Inferred from mutant phenotype
11158293 MGI
acts upstream of or within methionine biosynthetic process IMP
IMP: Inferred from mutant phenotype
11158293 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

methionine synthase

cobalamin-dependent methionine synthase

vitamin-B12 dependent methionine synthase

Related Agents

Pre-clinical Phase
Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-12892 SKI-178 99.29% Unkown
HY-156048 Trifluoromethyl-tubercidin Inhibitor 99.12% Unkown
HY-116688 2-Hydroxy-4-(methylthio)butyric acid 88.0% Unkown
HY-148953 MTR-106 99.40% Unkown
HY-W077219 Boc-L-Arg(Mtr)-OH 99.06% Unkown
HY-RS08815 MTR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17417 Terc Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18898 Mtr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25389 Mtr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mtr NCBI NCBI:4548