2. Gene
  3. Rbm10 - RNA binding motif protein 10 Gene

Rbm10 - RNA binding motif protein 10 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as MINAS-60; E430039K10Rik

Gene ID: 236732 | Gene type: protein coding

About Rbm10

Summary

Predicted to enable identical protein binding activity and miRNA binding activity. Acts upstream of or within negative regulation of RNA metabolic process; negative regulation of cell population proliferation; and positive regulation of smooth muscle cell apoptotic process. Predicted to be located in nuclear speck. Predicted to be part of protein-containing complex. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; oocyte; and sensory organ. Human ortholog(s) of this gene implicated in TARP syndrome. Orthologous to human RBM10 (RNA binding motif protein 10). [provided by Alliance of Genome Resources, Apr 2022]

Rbm10 Products(6)

mRNA Protein Name
NM_001167775.2 NP_001161247.1 RNA-binding protein 10 isoform 2
NM_001167776.2 NP_001161248.1 RNA-binding protein 10 isoform 3
NM_001358903.1 NP_001345832.1 RNA-binding protein 10 isoform 2
NM_001358904.1 NP_001345833.1 RNA-binding protein 10 isoform 4
NM_001358905.1 NP_001345834.1 RNA-binding protein 10 isoform 5
NM_145627.3 NP_663602.1 RNA-binding protein 10 isoform 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within 3'-UTR-mediated mRNA stabilization IDA
IDA: Inferred from direct assay
19508861 MGI
acts upstream of or within negative regulation of cell population proliferation IDA
IDA: Inferred from direct assay
19508861 MGI
acts upstream of or within negative regulation of mRNA splicing, via spliceosome IMP
IMP: Inferred from mutant phenotype
23636947 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
19508861 MGI
acts upstream of or within negative regulation of vascular associated smooth muscle cell proliferation IGI
IGI: Inferred from genetic interaction
19508861 MGI
acts upstream of or within positive regulation of vascular associated smooth muscle cell apoptotic process IDA
IDA: Inferred from direct assay
19508861 MGI
acts upstream of or within regulation of vascular associated smooth muscle cell apoptotic process IGI
IGI: Inferred from genetic interaction
19508861 MGI
acts upstream of vascular associated smooth muscle cell apoptotic process IDA
IDA: Inferred from direct assay
19508861 MGI
acts upstream of vascular associated smooth muscle cell proliferation IGI
IGI: Inferred from genetic interaction
19508861 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

RNA-binding protein 10

Ribosome biogenesis inhibitor MINAS-60

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-142032 RBM10-8 Inhibitor / Unkown
HY-RS11731 RBM10 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22768 Rbm10 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rbm10 NCBI NCBI:8241