2. Gene
  3. Vac14 - Vac14 homolog (S. cerevisiae) Gene

Vac14 - Vac14 homolog (S. cerevisiae) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Trx; ingls; Tax1bp2; D8Wsu151e

Gene ID: 234729 | Gene type: protein coding

About Vac14

Summary

Predicted to enable identical protein binding activity and kinase activator activity. Predicted to be involved in phosphatidylinositol biosynthetic process and positive regulation of kinase activity. Predicted to act upstream of or within response to osmotic stress. Predicted to be located in cytosol and vacuolar membrane. Predicted to be part of PAS complex. Predicted to be active in endosome membrane. Predicted to be extrinsic component of vacuolar membrane. Is expressed in embryo and extraembryonic component. Human ortholog(s) of this gene implicated in striatonigral degeneration. Orthologous to human VAC14 (VAC14 component of PIKfyve complex). [provided by Alliance of Genome Resources, Apr 2022]

Vac14 Products(1)

mRNA Protein Name
NM_146216.3 NP_666328.2 protein VAC14 homolog
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in regulation of postsynaptic neurotransmitter receptor internalization IDA
IDA: Inferred from direct assay
22842785 MGI
involved in regulation of postsynaptic neurotransmitter receptor internalization IMP
IMP: Inferred from mutant phenotype
22842785 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in presynaptic endosome IDA
IDA: Inferred from direct assay
22842785 MGI
is active in presynaptic endosome IMP
IMP: Inferred from mutant phenotype
22842785 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein VAC14 homolog

Tax1 (human T-cell leukemia virus type I) binding protein 1

Tax1 (human T-cell leukemia virus type I) binding protein 2

vacuole morphology 14

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15592 VAC14 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22907 Vac14 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vac14 NCBI NCBI:55697