2. Gene
  3. Smg1 - SMG1 nonsense mediated mRNA decay associated PI3K related kinase Gene

Smg1 - SMG1 nonsense mediated mRNA decay associated PI3K related kinase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mKIAA0421; 2610207I05Rik; 5430435M13Rik; C130002K18Rik

Gene ID: 233789 | Gene type: protein coding

About Smg1

Summary

Predicted to enable protein kinase C activity and telomeric DNA binding activity. Predicted to be involved in several processes, including TORC1 signaling; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; and protein phosphorylation. Predicted to act upstream of or within DNA repair and phosphorylation. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of TORC1 complex and TORC2 complex. Predicted to be active in nucleus. Is expressed in spermatid and spermatocyte. Orthologous to human SMG1 (SMG1 nonsense mediated mRNA decay associated PI3K related kinase). [provided by Alliance of Genome Resources, Apr 2022]

Smg1 Products(1)

mRNA Protein Name
NM_001031814.1 NP_001026984.1 serine/threonine-protein kinase SMG1
Gene Ontology
  • Cellular Component
Cellular Component GO Annotation Evidence Reference Source
located in chromatoid body IDA
IDA: Inferred from direct assay
32665638 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase SMG1

PI-3-kinase-related kinase SMG-1

SMG-1

SMG1 homolog, phosphatidylinositol 3-kinase-related kinase

lambda-interacting protein

lambda/iota protein kinase C-interacting protein

nonsense mediated mRNA decay-associated PI3K-related kinase SMG1

phosphatid

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-161111 KVS0001 Inhibitor 99.14% Unkown
HY-RS13430 SMG1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18791 Smg1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25280 Smg1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Smg1 NCBI NCBI:23049