2. Gene
  3. Eif2a - eukaryotic translation initiation factor 2A Gene

Eif2a - eukaryotic translation initiation factor 2A Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as D030048D22; D3Ertd194e

Gene ID: 229317 | Gene type: protein coding

About Eif2a

Summary

Predicted to enable RNA binding activity and ribosome binding activity. Acts upstream of or within SREBP signaling pathway; cellular protein metabolic process; and positive regulation of signal transduction. Predicted to be located in cytoplasm. Predicted to be part of cytosolic small ribosomal subunit and eukaryotic translation initiation factor 2 complex. Is expressed in brain; early conceptus; lens; liver; and ovary. Orthologous to human EIF2A (eukaryotic translation initiation factor 2A). [provided by Alliance of Genome Resources, Apr 2022]

Eif2a Products(3)

mRNA Protein Name
NM_001005509.3 NP_001005509.1 eukaryotic translation initiation factor 2A isoform 1
NM_001411292.1 NP_001398221.1 eukaryotic translation initiation factor 2A isoform 2
NM_001411293.1 NP_001398222.1 eukaryotic translation initiation factor 2A isoform 3
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within SREBP signaling pathway IDA
IDA: Inferred from direct assay
18852460 MGI
acts upstream of or within positive regulation of signal transduction IDA
IDA: Inferred from direct assay
18852460 MGI
acts upstream of or within protein phosphorylation IDA
IDA: Inferred from direct assay
16705175 MGI
acts upstream of or within translation IDA
IDA: Inferred from direct assay
7519779 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

eukaryotic translation initiation factor 2A

eIF-2A

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-119240 CCT020312 Activator 99.05% Unkown
HY-101991 ML291 99.74% Unkown
HY-145835A (S)-PERK-IN-5 Inhibitor / Unkown
HY-RS04241 EIF2A Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18997 Eif2a Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25486 Eif2a Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eif2a NCBI NCBI:83939