2. Gene
  3. Tubb4b - tubulin, beta 4B class IVB Gene

Tubb4b - tubulin, beta 4B class IVB Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Tubb2c; Tubb2c1; 4930542G03Rik

Gene ID: 227613 | Gene type: protein coding

About Tubb4b

Summary

Predicted to enable GTP binding activity and double-stranded RNA binding activity. Predicted to be a structural constituent of Cytoskeleton. Predicted to be involved in microtubule Cytoskeleton organization and mitotic cell cycle. Located in myelin sheath. Is expressed in brain ependyma; epithelial layer of oviduct; nasal epithelium; respiratory system epithelium; and seminiferous tubule. Human ortholog(s) of this gene implicated in Leber congenital amaurosis with early-onset deafness. Orthologous to human TUBB4B (tubulin beta 4B class IVb). [provided by Alliance of Genome Resources, Apr 2022]

Tubb4b Products(1)

mRNA Protein Name
NM_146116.2 NP_666228.1 tubulin beta-4B chain
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in flagellated sperm motility IDA
IDA: Inferred from direct assay
37295417 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in sperm flagellum IDA
IDA: Inferred from direct assay
37295417 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tubulin beta-4B chain

novel tubulin protein

tubulin beta-2C chain

tubulin, beta 2C

tubulin, beta 2c1

tubulin, beta, 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15256 TUBB4B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21214 Tubb4b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27730 Tubb4b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tubb4b NCBI NCBI:10383