2. Gene
  3. Hhat - hedgehog acyltransferase Gene

Hhat - hedgehog acyltransferase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Skn; AP-2CRE; 2810432O22Rik; Tg(TFAP2A-cre)1Will

Gene ID: 226861 | Gene type: protein coding

About Hhat

Summary

Enables palmitoyltransferase activity. Involved in N-terminal peptidyl-L-cysteine N-palmitoylation. Acts upstream of or within protein palmitoylation and smoothened signaling pathway. Predicted to be located in Golgi apparatus. Predicted to be active in endoplasmic reticulum. Is expressed in branchial arch; embryo; embryo ectoderm; and limb. Used to study chondrodysplasia-pseudohermaphroditism syndrome. Human ortholog(s) of this gene implicated in chondrodysplasia-pseudohermaphroditism syndrome. Orthologous to human HHAT (hedgehog Acyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Hhat Products(1)

mRNA Protein Name
NM_144881.5 NP_659130.2 protein-cysteine N-palmitoyltransferase HHAT precursor
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables palmitoyltransferase activity IMP
IMP: Inferred from mutant phenotype
15075292 MGI
Biological Process GO Annotation Evidence Reference Source
involved in N-terminal peptidyl-L-cysteine N-palmitoylation IMP
IMP: Inferred from mutant phenotype
15075292 MGI
acts upstream of or within protein palmitoylation IMP
IMP: Inferred from mutant phenotype
15075292 MGI
acts upstream of or within smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
15075292 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein-cysteine N-palmitoyltransferase HHAT

skinny hedgehog protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (8)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-18366A RU-SKI 43 hydrochloride Inhibitor 98.81% Unkown
HY-18366 RU-SKI 43 Inhibitor / Unkown
HY-123781A RUSKI-201 dihydrochloride Inhibitor 98.20% Unkown
HY-161175 IMP-1575 Inhibitor / Unkown
HY-RS06157 HHAT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-123781 RUSKI-201 Inhibitor / Unkown
HY-RS20752 Hhat Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27264 Hhat Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hhat NCBI NCBI:55733