2. Gene
  3. Trpm6 - transient receptor potential cation channel, subfamily M, member 6 Gene

Trpm6 - transient receptor potential cation channel, subfamily M, member 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CHAK2; TRPM6/CHAK2

Gene ID: 225997 | Gene type: protein coding

About Trpm6

Summary

Enables cation channel activity. Acts upstream of or within metal ion transport. Located in apical plasma membrane and brush border membrane. Is expressed in several structures, including cochlea; colon; extraembryonic component; ganglia; and genitourinary system. Human ortholog(s) of this gene implicated in intestinal hypomagnesemia 1 and metal metabolism disorder. Orthologous to human TRPM6 (transient receptor potential cation channel subfamily M member 6). [provided by Alliance of Genome Resources, Apr 2022]

Trpm6 Products(1)

mRNA Protein Name
NM_153417.2 NP_700466.1 transient receptor potential cation channel subfamily M member 6
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables monoatomic cation channel activity IDA
IDA: Inferred from direct assay
14576148 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within metal ion transport IDA
IDA: Inferred from direct assay
14576148 MGI
Cellular Component GO Annotation Evidence Reference Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
14576148 MGI
located in brush border membrane IDA
IDA: Inferred from direct assay
14576148 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transient receptor potential cation channel subfamily M member 6

melastatin-related TRP cation channel 6

putative cation channel subfamily M member 6

transient receptor potential cation channel 6/channel-kinase 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-103073 Mesendogen Inhibitor 99.84% Unkown
HY-RS15116 TRPM6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20503 Trpm6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27011 Trpm6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trpm6 NCBI NCBI:140803