2. Gene
  3. Fhod3 - formin homology 2 domain containing 3 Gene

Fhod3 - formin homology 2 domain containing 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as FHOS2; mKIAA1695; A930009H06Rik

Gene ID: 225288 | Gene type: protein coding

About Fhod3

Summary

Predicted to enable actin filament binding activity. Acts upstream of or within actin Cytoskeleton organization and negative regulation of actin filament polymerization. Located in sarcomere. Is expressed in several structures, including axial skeleton; central nervous system; gut; heart; and metanephros. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy. Orthologous to human FHOD3 (formin homology 2 domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]

Fhod3 Products(4)

mRNA Protein Name
NM_001289654.1 NP_001276583.1 FH1/FH2 domain-containing protein 3 isoform 2
NM_001289655.1 NP_001276584.1 FH1/FH2 domain-containing protein 3 isoform 3
NM_001403900.1 NP_001390829.1 FH1/FH2 domain-containing protein 3 isoform 4
NM_175276.4 NP_780485.2 FH1/FH2 domain-containing protein 3 isoform 1
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cardiac myofibril assembly IMP
IMP: Inferred from mutant phenotype
23213483 MGI
acts upstream of or within negative regulation of actin filament polymerization IDA
IDA: Inferred from direct assay
19706596 MGI
acts upstream of or within sarcomere organization IGI
IGI: Inferred from genetic interaction
19706596 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

FH1/FH2 domain-containing protein 3

formin homolog overexpressed in spleen 2

formin-family protein FHOS2

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04939 FHOD3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS22507 Fhod3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fhod3 NCBI NCBI:80206