Tfb1m - transcription factor B1, mitochondrial Gene

Mus musculus

Also known as mtTFB1

Gene ID: 224481 | Gene type: protein coding

About Tfb1m

Summary

Predicted to enable mitochondrial transcription factor activity and rRNA (adenine-N6,N6-)-dimethyltransferase activity. Predicted to be involved in rRNA methylation and transcription initiation from mitochondrial promoter. Predicted to act upstream of or within methylation. Located in mitochondrion. Is expressed in early conceptus and secondary oocyte. Orthologous to human TFB1M (transcription factor B1, mitochondrial). [provided by Alliance of Genome Resources, Apr 2022]

Tfb1m Products(1)

mRNA	Protein	Name
NM_146074.3	NP_666186.1	dimethyladenosine transferase 1, mitochondrial

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables S-adenosyl-L-methionine binding	IDA IDA: Inferred from direct assay	23804760	MGI
enables rRNA (adenine-N6,N6-)-dimethyltransferase activity	IMP IMP: Inferred from mutant phenotype	19356719	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in rRNA methylation	IMP IMP: Inferred from mutant phenotype	19356719	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

dimethyladenosine transferase 1, mitochondrial

S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1

mitochondrial 12S rRNA dimethylase 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14413	TFB1M Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21785	Tfb1m Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Tfb1m	NCBI	NCBI:51106

Name
Email *

	Sorry, but the email address you supplied was invalid.