2. Gene
  3. Adcy5 - adenylate cyclase 5 Gene

Adcy5 - adenylate cyclase 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ac5

Gene ID: 224129 | Gene type: protein coding

About Adcy5

Summary

Enables Adenylate Cyclase activity; Adenylate Cyclase binding activity; and scaffold protein binding activity. Acts upstream of or within G protein-coupled receptor signaling pathway; locomotory behavior; and neuromuscular process controlling balance. Located in cilium and plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study Parkinson's disease. Orthologous to human ADCY5 (Adenylate Cyclase 5). [provided by Alliance of Genome Resources, Apr 2022]

Adcy5 Products(1)

mRNA Protein Name
NM_001012765.5 NP_001012783.3 adenylate cyclase type 5
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables adenylate cyclase activity IDA
IDA: Inferred from direct assay
17593019 MGI
enables adenylate cyclase activity IMP
IMP: Inferred from mutant phenotype
12223546 MGI
enables adenylate cyclase binding IPI
IPI: Inferred from physical interaction
18164588 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
17593019 MGI
enables scaffold protein binding IPI
IPI: Inferred from physical interaction
19574217 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within G protein-coupled adenosine receptor signaling pathway IGI
IGI: Inferred from genetic interaction
12223546 MGI
acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway IGI
IGI: Inferred from genetic interaction
12223546 MGI
acts upstream of or within adenylate cyclase-activating dopamine receptor signaling pathway IGI
IGI: Inferred from genetic interaction
12223546 MGI
acts upstream of or within adenylate cyclase-inhibiting dopamine receptor signaling pathway IGI
IGI: Inferred from genetic interaction
12223546 MGI
acts upstream of or within locomotory behavior IMP
IMP: Inferred from mutant phenotype
12665504 MGI
acts upstream of or within neuromuscular process controlling balance IMP
IMP: Inferred from mutant phenotype
12665504 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cilium IDA
IDA: Inferred from direct assay
21670265 MGI
located in membrane IDA
IDA: Inferred from direct assay
17593019 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
12665504 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adenylate cyclase type 5

ATP pyrophosphate-lyase 5

adenylate cyclase type V

adenylyl cyclase 5

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00331 ADCY5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22379 Adcy5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28903 Adcy5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adcy5 NCBI NCBI:111