2. Gene
  3. Trpv2 - transient receptor potential cation channel, subfamily V, member 2 Gene

Trpv2 - transient receptor potential cation channel, subfamily V, member 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as GRC; Vrl1; VRL-1; OTRPC2

Gene ID: 22368 | Gene type: protein coding

About Trpv2

Summary

Enables Calcium Channel activity. Involved in positive regulation of axon extension; positive regulation of calcium ion import; and positive regulation of cold-induced thermogenesis. Located in cell body; cell surface; and growth cone. Is expressed in central nervous system; dorsal root ganglion; sensory organ; and testis. Orthologous to human TRPV2 (transient receptor potential cation channel subfamily V member 2). [provided by Alliance of Genome Resources, Apr 2022]

Trpv2 Products(5)

mRNA Protein Name
NM_001382489.1 NP_001369418.1 transient receptor potential cation channel subfamily V member 2 isoform 2
NM_001382490.1 NP_001369419.1 transient receptor potential cation channel subfamily V member 2 isoform 3
NM_001382491.1 NP_001369420.1 transient receptor potential cation channel subfamily V member 2 isoform 4
NM_001382492.1 NP_001369421.1 transient receptor potential cation channel subfamily V member 2 isoform 5
NM_011706.2 NP_035836.2 transient receptor potential cation channel subfamily V member 2 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables calcium channel activity IDA
IDA: Inferred from direct assay
10559903 MGI
enables monoatomic cation channel activity IDA
IDA: Inferred from direct assay
10559903 MGI
Biological Process GO Annotation Evidence Reference Source
NOT involved in apoptotic process IDA
IDA: Inferred from direct assay
20357111 MGI
involved in positive regulation of axon extension IMP
IMP: Inferred from mutant phenotype
20357111 MGI
involved in positive regulation of calcium ion import IMP
IMP: Inferred from mutant phenotype
20357111 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: Inferred from mutant phenotype
26882545 MGI
Cellular Component GO Annotation Evidence Reference Source
located in axon IDA
IDA: Inferred from direct assay
20357111 MGI
located in axonal growth cone IDA
IDA: Inferred from direct assay
20357111 MGI
located in cell body IDA
IDA: Inferred from direct assay
20357111 MGI
located in cell surface IDA
IDA: Inferred from direct assay
20357111 MGI
located in growth cone membrane IDA
IDA: Inferred from direct assay
20357111 MGI
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
10559903 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
10559903 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transient receptor potential cation channel subfamily V member 2

growth factor regulated channel

growth factor-regulated calcium channel

osm-9-like TRP channel 2

vanilloid receptor-like protein 1

Related Agents

Approval
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0545 Probenecid 99.92% Yes
Pre-clinical Phase
Bioactive Molecules (10)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-132222 SET2 Antagonist 99.78% Unkown
HY-157131 TRPV2-selective blocker 1 Inhibitor 99.84% Unkown
HY-N8264 Moringin Agonist 99.95% Unkown
HY-B0545R Probenecid (Standard) 99.00% Unkown
HY-W404916 Probenecid sodium 99.37% Unkown
HY-RS15122 TRPV2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-B0545S Probenecid-d14 99.0% Unkown
HY-RS17234 Trpv2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N3230 Murpanicin Inhibitor / Unkown
HY-RS23687 Trpv2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trpv2 NCBI NCBI:51393