2. Gene
  3. Uqcrq - ubiquinol-cytochrome c reductase, complex III subunit VII Gene

Uqcrq - ubiquinol-cytochrome c reductase, complex III subunit VII Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Qpc; QP-C; Uqcrb; c1502; 9.5kDa; 1100001F06Rik; 1500040F11Rik; 5830407L17Rik

Gene ID: 22272 | Gene type: protein coding

About Uqcrq

Summary

Predicted to enable ubiquinol-cytochrome-c reductase activity. Acts upstream of or within brain development. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; integumental system; and nervous system. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 4. Orthologous to human UQCRQ (ubiquinol-cytochrome c reductase complex III subunit VII). [provided by Alliance of Genome Resources, Apr 2022]

Uqcrq Products(2)

mRNA Protein Name
NM_001326614.1 NP_001313543.1 cytochrome b-c1 complex subunit 8
NM_025352.3 NP_079628.1 cytochrome b-c1 complex subunit 8
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
32161263 MGI
Biological Process GO Annotation Evidence Reference Source
involved in cerebellar Purkinje cell layer development IEP
IEP: Inferred from expression pattern
16901643 MGI
involved in hippocampus development IEP
IEP: Inferred from expression pattern
16901643 MGI
involved in hypothalamus development IEP
IEP: Inferred from expression pattern
16901643 MGI
involved in midbrain development IEP
IEP: Inferred from expression pattern
16901643 MGI
involved in pons development IEP
IEP: Inferred from expression pattern
16901643 MGI
involved in pyramidal neuron development IEP
IEP: Inferred from expression pattern
16901643 MGI
involved in subthalamus development IEP
IEP: Inferred from expression pattern
16901643 MGI
involved in thalamus development IEP
IEP: Inferred from expression pattern
16901643 MGI
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrion IDA
IDA: Inferred from direct assay
16120479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytochrome b-c1 complex subunit 8

complex III subunit 8

complex III subunit VII

complex III subunit VIII

low molecular mass ubiquinone-binding protein (Qpc-pending)

ubiquinol-cytochrome c reductase binding protein

ubiquinol-cytochrome c reductase complex 9.5 kDa protein

ubiquinol-cy

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15503 UQCRQ Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22897 Uqcrq Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29411 Uqcrq Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Uqcrq NCBI NCBI:27089