Uox - urate oxidase Gene

Mus musculus

Gene ID: 22262 | Gene type: protein coding

About Uox

Summary

Enables urate oxidase activity. Involved in allantoin metabolic process; purine-containing compound catabolic process; and urate catabolic process. Located in mitochondrion. Is active in peroxisome. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; respiratory system; and sensory organ. Used to study hyperuricemia; kidney disease; and nephrogenic diabetes insipidus. Orthologous to human UOX (urate oxidase (pseudogene)). [provided by Alliance of Genome Resources, Apr 2022]

Uox Products(1)

mRNA	Protein	Name
NM_009474.5	NP_033500.1	uricase

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables urate oxidase activity	IDA IDA: Inferred from direct assay	4207016	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in AMP catabolic process	IDA IDA: Inferred from direct assay	16462750	MGI
involved in GMP catabolic process	IDA IDA: Inferred from direct assay	16462750	MGI
involved in IMP catabolic process	IDA IDA: Inferred from direct assay	16462750	MGI
involved in adenosine catabolic process	IDA IDA: Inferred from direct assay	16462750	MGI
involved in allantoin metabolic process	IDA IDA: Inferred from direct assay	4207016	MGI
involved in amide catabolic process	IDA IDA: Inferred from direct assay	4207016	MGI
involved in dAMP catabolic process	IDA IDA: Inferred from direct assay	16462750	MGI
involved in dGMP catabolic process	IDA IDA: Inferred from direct assay	16462750	MGI
involved in deoxyadenosine catabolic process	IDA IDA: Inferred from direct assay	16462750	MGI
involved in deoxyguanosine catabolic process	IDA IDA: Inferred from direct assay	16462750	MGI
involved in deoxyinosine catabolic process	IDA IDA: Inferred from direct assay	16462750	MGI
involved in guanine catabolic process	IDA IDA: Inferred from direct assay	16462750	MGI
involved in hypoxanthine catabolic process	IDA IDA: Inferred from direct assay	16462750	MGI
involved in inosine catabolic process	IDA IDA: Inferred from direct assay	16462750	MGI
involved in urate catabolic process	IDA IDA: Inferred from direct assay	16462750	MGI
involved in xanthine catabolic process	IDA IDA: Inferred from direct assay	4207016	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
is active in peroxisome	IDA IDA: Inferred from direct assay	3200253	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

uricase

Related Agents

Pre-clinical Phase

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P2921	Urate oxidase, Microorganism		90.00%	Unkown
HY-P2921C	Uricase (Recombinant)		/	Unkown
HY-P2921A	Uricase, Bacillus fastidious		/	Unkown
HY-P2921B	Uricase, Arthrobacter globiformis		/	Unkown
HY-RS16362	UOX Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS19304	Uox Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS25795	Uox Rat Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Uox	NCBI	NCBI:391051

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