2. Gene
  3. Ube2m - ubiquitin-conjugating enzyme E2M Gene

Ube2m - ubiquitin-conjugating enzyme E2M Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as UBC12; Ubc-rs2; 2510040H03Rik

Gene ID: 22192 | Gene type: protein coding

About Ube2m

Summary

Predicted to enable NEDD8 transferase activity and ubiquitin-protein transferase activity. Predicted to be involved in positive regulation of neuron apoptotic process and protein neddylation. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and hemolymphoid system gland. Orthologous to human UBE2M (Ubiquitin Conjugating Enzyme E2 M). [provided by Alliance of Genome Resources, Apr 2022]

Ube2m Products(3)

mRNA Protein Name
NM_001168469.2 NP_001161941.1 NEDD8-conjugating enzyme Ubc12 isoform 2
NM_001243968.1 NP_001230897.1 NEDD8-conjugating enzyme Ubc12 isoform 3
NM_145578.3 NP_663553.1 NEDD8-conjugating enzyme Ubc12 isoform 1
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in regulation of postsynapse assembly EXP
EXP: Inferred from Experiment
25581363 MGI
involved in regulation of postsynapse assembly IDA
IDA: Inferred from direct assay
25581363 MGI
involved in regulation of postsynapse assembly IMP
IMP: Inferred from mutant phenotype
25581363 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in glutamatergic synapse EXP
EXP: Inferred from Experiment
25581363 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
25581363 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
25581363 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
25581363 MGI
is active in postsynapse IEP
IEP: Inferred from expression pattern
25581363 MGI
is active in presynapse IDA
IDA: Inferred from direct assay
25581363 MGI
is active in presynapse IEP
IEP: Inferred from expression pattern
25581363 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NEDD8-conjugating enzyme Ubc12

NEDD8 carrier protein

NEDD8 protein ligase

UBC12 homolog, yeast

ubiquitin C, related sequence 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-111505 NAcM-OPT Inhibitor 99.65% Unkown
HY-RS15355 UBE2M Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19492 Ube2m Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25986 Ube2m Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ube2m NCBI NCBI:9040